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A corneal inlay (also called an intracorneal implant) is a device which is surgically implanted in the cornea of the eye as a treatment for presbyopia. Successful installation results in reducing dependence on reading glasses, so that the user can more easily engage in everyday tasks such as using a mobile phone, reading store shelf prices and working on a computer. Coreal inlays are small, thin, and permeable. Typically one is implanted in the non-dominant eye. Jose Barraquer created the first corneal inlay prototype in 1949 in Barcelona, Spain. The flint glass material which he used, however, was found to be unsuitable because of biocompatibility issues.〔Whitman, Jeffrey. ("Corneal inlays provide safe, reversible option for presbyopia treatment." ) ''Ocular Surgery News U.S. Edition'' 2012 Aug.〕 Other transparent, permeable materials were tested, including hydrogel polymers in the 1960’s.〔 Some early corneal inlay recipients experienced complications, such as corneal opacification, thinning and melting. Researchers soon found that, as well as the material, the thickness of the inlay and the depth at which it was implanted were important, as well as permeability and centration. There was a delay in the general introduction of the treatment while considerable research was done to find safe and reliable combinations of these factors.〔 In 2014, the use of a corneal inlay for treatment of presbyopia has not been approved United States. However, the inlays are in commercial use in some countries in Europe, Asia-Pacific, the Americas and the Middle East. The inlays are implanted into the cornea either in a laser-created corneal pocket or lamellar corneal flap (similar to LASIK). The inlays can be removed should the patient develop another condition requiring medical treatment.〔 Currently there are four corneal inlays in use: The KAMRAinlay (AcuFocus, Inc.) is a biocompatible ring that increases the visual depth of field using the physical principle of a small aperture,. This design only allows focused light to enter the eye resulting in an improvement in near and intermediate vision while maintaining distance vision.〔 The FlexivueMicrolens (PresbiaCoöperatief U.A.) is a refractive hydrophilic polymer lens. The central zone of the lens is free of refractive power and the peripheral zone has a standard positive refractive power. This inlay works on a similar principle to bifocal glasses. The bifocal design provides two images to the retina simultaneously. Each specific point of focus is delivered as both a sharp and a blurred image. The FlexivueMicrolens is available in a variety of powers, and can be exchanged as presbyopia progresses. The Raindrop Near Vision Inlay (also known as Vue+ and Presbylens) (Revision Optics, Inc.) is a micro-porous hydrogel inlay that creates a microscopic change to the curvature in the center of the cornea, resulting in a multifocal cornea designed to support near and intermediate focusing power. The Icolens System (Neoptics AG) is another refractive hydrophilic polymer lens, similar to the Flexivue Microlens, with no power in the center and the peripheral zone has positive refractive power. This inlay is also available in assorted powers, which may be exchanged as required due to the progression of presbyopia.〔("Advances in the Surgical Correction of Presbyopia" ). ''Medscape'' (free account needed for access)〕(【引用サイトリンク】url=http://bmctoday.net/crstoday/2013/06/article.asp?f=corneal-inlays-current-and-future-designs ) == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Corneal inlay」の詳細全文を読む スポンサード リンク
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